Preimplantation Genetic Screening
Since the study of produced embryos in vitro revealed a high rate of chromosomal aneuploidy. Most types of aneuploidy are not compatible with life, regarding these most common syndromes caused by non-sex chromosome aneuploidy including Down syndrome, Edwards syndrome, and Patau syndrome.
Aneuploidy is usually not inherited and can involve any chromosome. In addition, the embryos that derived from advanced reproductive age mothers have significant incident of chromosomal mutation.