Intra-cytoplasmic Morphologically Selected Sperm Injection

    What is IMSI by Leica?

    IMSI is a real-time method where sperms are selected before the microinjection takes place. This is done using an inverted microscope that is able to provide a much greater magnifying power (around 6,000 times) than those that are normally used in reproductive laboratories (400 times) to carry out the ICSI.

    Why perform IMSI by Leica?

    • To choose good quality sperm
    • Improve fertilization and normal embryo development
    • Reduce miscarriage rate
    • Increase pregnancy rate

    How IMSI by Leica works?

    Washed sperm are viewed at a magnification 6000-12,000 times than their normal size. This greater magnification shows irregular features in sperm heads that otherwise cannot be seen. The embryologist then chooses sperm with the most normal looking heads.

    ​Who can benefit from IMSI by Leica?

    • Men with poor sperm morphology because poor morphology makes sperm more susceptible to oxidation damage.
    • Men with a higher level of DNA fragmentation in their sperm (DNA fragmentation is a sign of oxidation damage).
    • Couples with few embryos developing to the blastocyst stage.
    • Couples who have not become pregnant despite the transfer of several reasonable quality embryos.