Intracytoplasmic Sperm Injection (ICSI) is a specialized form of In Vitro Fertilization (IVF) that is used for the treatment of severe cases of male factor infertility. ICSI involves the injection of a single sperm directly into a mature egg.

    IVF/ICSI process

    Before ICSI can be done, mature eggs must be retrieved from the female partner during a standard IVF cycle.  The male partner’s semen sample is prepared in the lab to isolate as many healthy moving sperm as possible.

    After allowing the eggs to rest for two to three hours following their removal, the tight outer coating of cells (cumulus) is removed from each egg.  Only then can we be sure the egg is mature enough to undergo ICSI.

    Immature eggs cannot be injected. However, they can be incubated for a further two to six hours and reassessed. If they mature in that time they can still be injected along with the other mature eggs. A special instrument is used to hold the egg in place. It is so small you can barely see the tip with the naked eye.

    A thinner, sharp, needle-like instrument is used to pick up a single normal appearing sperm. With great precision, the needle is inserted through the egg’s outer coating (the zona pellucida) and into the egg itself. The sperm is slowly injected into the egg, and the needle is removed, leaving the sperm behind.

    The injected eggs are placed in an incubator overnight and checked the next morning for signs of fertilisation.

    After an additional 24 hours, we can determine how many have divided and gone on to form embryos. Not all eggs fertilise, and not all fertilised eggs become embryos. As with standard IVF, the number of embryos replaced into the uterus depends on the woman’s age and medical history.

    Provided they appear healthy, additional embryos can be frozen if desired. The potential improvement in fertility that this type of treatment may yield depends on the woman’s age, diagnosis and the initial male semen analysis, and should be discussed with your specialist

    Who is IVF/ICSI Recommended for?

    Couples who have had poor or no fertilisation during standard IVF, as well as men who have:

    • poor sperm morphology (abnormally shaped sperm)
    • poor sperm motility (slow moving sperm)
    • a low sperm count
    • an obstruction which prevents sperm release, such as vasectomy
    • anti-sperm antibodies (antibodies produced by the man’s body that may inhibit sperm function)
    • a vasectomy reversal that was unsuccessful or resulted in a very low sperm count or very poor quality sperm

    Preparation Steps

    Step 1

    Consultation with our IVF counselor

    You can book an appointment with a Fertility Specialist
    by calling 02 252 3833 or contact our website at
    www.safefertilitycenter.com At your initial appointment,
    your Personal Assistant will carry out some preliminary
    investigations and give you an overview of possible
    treatments. There are many treatment options available
    and not everyone will require IVF to achieve a
    pregnancy.

    Step 2

    Registration and Preliminary Investigations

    If your Personal Assistant does recommend IVF
    treatment, they will give you a registration form, to be
    completed and returned to us. During your initial visit,
    your Fertility Specialist may refer you for the
    following tests:

    • blood tests for both partners
    • ultrasound for the female partner
    • semen analysis for the male partner

    Step 3

    Getting Started

    You make contact with your Personal Assistant who will
    arrange a block appointment for your preliminary
    investigations, mandatory counseling and payment
    information session.

    Step 4

    Obtain a National Police Record Check and Child Protection Order
    Check

    You and your partner must complete
    consent forms for allowing us to proceed on
    IVF treatment

    Step 5

    Confirm treatment plan with your Personal Assistant

    When your test results are available, your
    Personal Assistant will meet with you to
    confirm the appropriate treatment option.

    Step 6

    Begin IVF Treatment