When do I start taking the drugs?
You will to start once you are confirmed to the program.
How do I take it?
The medication can either be administered subcutaneously by injection or via inhalation by nasal spray. You will appoint a session with one of our nurse will provide you clear instructions on how to correctly and safely administer the prescribed medication at home.
It is important that the medication is taken on the same time each day.
When should I stop taking the Buserelin/Nafarelin?
These medications should be taken continuously, until you are prescribed with an hCG injection. This will be 2 days before your egg retrieval.
What side effects should I be expecting?
After taking the medication to ‘switch off’ your ovaries and you may experience headaches, hot flushes, forgetfulness and mild depression. Some patient may experience slight or heavy vaginal bleeding. This is not to be alarm, since this are the common adverse reaction during this stage of treatment.
Where do I keep the Buserelin/Nafarelin?
The medication should be kept in the fridge or a cool place away from direct heat or sunlight. These medications can be stored for a long period of time, but it is advice to regularly check the expiry date on the bottle before used. All used medication should be disposed of at the end of your treatment cycle and not kept for subsequent treatment cycles.
Stimulating the ovaries
Follicle Stimulating Hormone injections (Menopur) stimulate the ovaries to produce eggs. Menopur is administered by a daily injection under the skin (subcutaneous). Follicles are tiny fluid filled sacs that grow on the ovary and contain the eggs. In your normal monthly cycle, only one egg is produced. To increase the chances of pregnancy with IVF treatment, we need several eggs. The average number of eggs retrieved is eight. Our nurse will teach you or your partner to administer the injections. Some couples are surprised to hear this, but it really is simple to learn, and much easier than having to visit your doctor every day. If you choose not to administer your own injections and wish to go to your nurse, you must make arrangements for this yourself, remembering that some injections have to be given at weekends or evenings. Unfortunately, we cannot arrange for injections to be given in the unit as we do not have the staff available. We are happy to teach whomever you wish, such as a relative or a friend, the injection technique. We will also supply you with the needles and syringes you need. We will provide a special container for the disposal of used needles and glass. Please do not put these in your household rubbish.
When do I start taking the Menopur injections?
The expected date for you to start the injections is given on your treatment program. The date will be confirmed once we are sure that the Buserelin or Nafarelin has been effective.
How is it taken?
We will arrange an appointment to teach you or your partner to give these injections. We will ensure that you can do it properly before your treatment begins.
Preparing an injection
- Ensure that all the contents of the dilutant ampoule are in the main body of the ampoule and not in the neck of the ampoule. Break off top of the ampoule. Remove the blue cover from the powder vials.
- Draw up dilutant into syringe using the green needle.
- Syringe the dilutant into the first vial of powder (Menopur). It will dissolve immediately. There is no need to shake the vial.
- Draw the mixture back into the syringe and repeat the same process with the remaining powder vials.
- Change the needle to the orange needle. Hold the syringe upright with the needle pointing upwards and gently tap out any air bubbles. Slowly push the fluid up the syringe until a drop of fluid appears at the top of the needle.
Giving the injection
- Give injection into correct sites shown during your injection teaching. Menopur –thigh or abdomen Use alternate sites.
- It is better to sit or lie down while the injection is given and to stay resting for five minutes afterwards, to prevent soreness and stiffness at the injection site.
How often do I take it?
The injection is given once each day and should be given at about the same time each day, preferably in the morning.
Disposing of Sharps
All needles, drug ampoules, and syringes must be disposed safely. You will be given a disposal box for this. Please bring it back to the clinic for proper disposal – Do not place in domestic waste.
When do I stop taking it?
We will tell you when to stop taking the injections or to change the dose, depending on your scan and blood test results.
What are the side effects?
You may get a reaction at the site of the injections. This can be redness, swelling or stiffness. This is normal and if one leg becomes worse than the other, rest that leg and have the injection in the other leg for a couple of days. Use alternate sites to prevent soreness. If you have a severe local reaction or experience flu like symptoms, please contact the nurses on +66 2525 3833-5. FSH injections may cause mild abdominal discomfort as the eggs start to grow in the follicles in the ovary. You may also find that your stomach becomes swollen at this time. You may experience some increase in vaginal discharge, upset tummy and mood swings.